Dear Team,
Where to find tractability_buckets file in the latest version, for example, version:22.11?
http://ftp.ebi.ac.uk/pub/databases/opentargets/platform/latest/input/
tractability_buckets-2021-03-08.tsv
Meanwhile, do we have a webpage for the details for each column name? for example:
[1] “ensembl_gene_id” “symbol”
[3] “accession” “Entry”
[5] “name” “Protein”
[7] “names” “IDG_family”
[9] “IDG_dtoclass” “IDG_tdl”
[11] “IDG_fam” “GO_BioProcess”
[13] “GO_MolFunction” “SM_B1_Approved”
[15] “Drug” “SM_B2_Advanced”
[17] “Clinical” “SM_B3_Phase”
[19] “1” “Clinical_1”
[21] “SM_B4_Structure” “with”
[23] “Ligand” “SM_B5_High-Quality”
[25] “Ligand_1” “SM_B6_High-Quality”
[27] “Pocket” “SM_B7_Med-Quality”
[29] “Pocket_1” “SM_B8_Druggable”
[31] “Family” “Bucket_sum_sm”
[33] “Top_bucket_sm” “drug_chembl_ids_sm”
[35] “drug_names_sm” “clinical_phases_sm”
[37] “PDB_Known_Ligand” “PDB_other”
[39] “High_Quality_ChEMBL_compounds” “DrugEBIlity_score”
[41] “Small_Molecule_Druggable_Genome_Member” “Category_sm”
[43] “Clinical_Precedence_sm” “Discovery_Precedence_sm”
[45] “Predicted_Tractable_sm” “drug_names_dict_sm”
[47] “clinical_phases_dict_sm” “AB_B1_Approved”
[49] “Drug_1” “AB_B2_Advanced”
[51] “Clinical_2” “AB_B3_Phase”
[53] “1_1” “Clinical_3”
[55] “AB_B4_UniProt” “loc”
[57] “high” “conf”
[59] “AB_B5_GO” “CC”
[61] “high_1” “conf_1”
[63] “AB_B6_UniProt” “loc_1”
[65] “med” “conf_2”
[67] “AB_B7_UniProt” “SigP”
[69] “or” “TMHMM”
[71] “AB_B8_GO” “CC_1”
[73] “med_1” “conf_3”
[75] “AB_B9_Human” “Protein_1”
[77] “Atlas” “loc_2”
[79] “Bucket_sum_ab” “Top_bucket_ab”
[81] “drug_chembl_ids_ab” “drug_names_ab”
[83] “clinical_phases_ab” “Uniprot_high_conf_loc”
[85] “GO_high_conf_loc” “Uniprot_med_conf_loc”
[87] “GO_med_conf_loc” “Gene”
[89] “ontology” “(cellular”
[91] “component)” “Transmembrane”
[93] “Signal_peptide” “HPA_main_location”
[95] “Clinical_Precedence_ab” “Predicted_Tractable_ab_High_confidence”
[97] “Predicted_Tractable_ab_Medium_to_low_confidence” “Category_ab”
[99] “drug_names_dict_ab” “clinical_phases_dict_ab”
[101] “PR_B1_Approved” “Drug_2”
[103] “PR_B2_Advanced” “Clinical_4”
[105] “PR_B3_Phase” “1_2”
[107] “Clinical_5” “PR_B4_Literature”
[109] “PR_B5_UniProt” “Ubiquitination”
[111] “PR_B6_Database” “Ubiquitination_1”
[113] “PR_B7_Half-life” “Data”
[115] “PR_B8_Small” “Molecule”
[117] “Binder” “Bucket_sum_PROTAC”
[119] “Top_bucket_PROTAC” “PR_locB_Location”
[121] “Score” “mentioned_in_PROTAC_literature”
[123] “literature_count_PROTAC” “pub_id”
[125] “full_id” “title”
[127] “Max_halflife” “Min_halflife”
[129] “Uniprot_keyword” “Uniprot_PTM”
[131] “Uniprot_CrossLink” “Ub_PhosphoSitePlus”
[133] “Ub_mUbiSiDa_2013” “number_of_ubiquitination_sites”
[135] “Bcell_mean” “NKcell_mean”
[137] “Hepatocytes_mean” “MouseNeuorons_mean”
[139] “count_compound_chembl_ids_PROTAC” “Clinical_Precedence_PROTAC”
[141] “Literature_Precedence_PROTAC” “Discovery_Opportunity_PROTAC”
[143] “Category_PROTAC” “OC_B1_Approved”
[145] “Drug_3” “OC_B2_Advanced”
[147] “Clinical_6” “OC_B3_Phase”
[149] “1_3” “Clinical_7”
[151] “Bucket_sum_othercl” “Top_bucket_othercl”
[153] “drug_chembl_ids_othercl” “drug_names_othercl”
[155] “clinical_phases_othercl” “Clinical_Precedence_othercl”
[157] “Category_othercl” “drug_names_dict_othercl”
[159] “clinical_phases_dict_othercl”
Thanks.
Shicheng