Where to access PROTAC data?

Data Access
1

Hello,

I’m interested in looking at PROTAC data mentioned in this blog post: The PROTACtable Genome: assessing drug target tractability. When I try to find this data in “Tractability” section, it doesn’t seem to have included PROTAC modality yet, my question is: has this data been integrated into Open Targets platform yet and is “Tractability” section the right place to find it?
Thank you.

Best,
Ying

2

Hi @vyx! :wave:

Welcome to the Open Targets Community! :tada:

The PROTAC data has not yet been integrated into the Open Targets Platform user interface. However, you can find the tractability pipeline output TSV file — tractability_buckets-2021-06-03.tsv — in our FTP server. Within the file, look for the columns ending with _PROTAC.

For more information on the tractability pipeline, including descriptions of the PROTAC assessments and underlying data supporting the assessment, please visit the pipeline GitHub repo.

Cheers,

Andrew :slight_smile:

3

Thank you Andrew! This is really helpful :grinning: