Dear Team,
I just learned that Genebass website have some bugs to handle P=0 which means lots of very significant association are not included/filtered in their website.
Hopefully, OT team could have some coordination with Genebass to fix the bug.
Best,
Shicheng
Hi @Shicheng_Guo,
Thank you for notifying us about the P=0 issue in Genebass.
We’re aware of this and attribute it to float overflow. To account for it, we assign these cases the smallest p-value observed in the significant Genebass results so that the evidence is not lost and is appropriately scored.
To be honest, I am more familiar with their raw data than with their website. So I’d really appreciate your input if there is any particular association that we could take as an example.
Best,
Irene
Fantastic!! I want to acknowledge that Open Targets team is Top 1 team in human genetic insights generation!!
