- For some genetic markers the posterior probability is low but LG2
score is high, they go opposite direction, how to interpret result? - I notice that sometimes when I look one variant and then
other the part of molQTL remains unchanged so sometimes I do the mistake
thinking that they have the same molQTLs. It is for both Safari and
Chrome browsers. Then for some markers the molQTLs referring to the
eQTLs do not appears even if I know that they are but for other
variants the molQTL deriving from eQTLs appears but pQTLs not. It
has
happened that for one of my markers I saw one time tuQTLs but when I
returned to the page they disappeared and now I see just one pQTL. - I have one question referring to the Open Targets old
version, if
for the drug association I see the Odds Ratio 2.0 it means that the
drug work more efficiently? - Of course I see still benefits coming from the old version
of Open
Targets, and I really don’t know what I will do without it my
work.
I like very much the new Open Targes but the hypothesis independent genetic data are more discovery for me.
Thank you for all your work with the platform, I started many years ago with Immunobase and saw all the transformation in these years.