Thanks for your response, @irene ! It’s very helpful. I agree that the definitions could be made more helpful. Please also consider to improve the formulas of the association scores calculation, espeially the harmonic sum in drugs-based records (my other question on this is here).
when a target is marked as being part of the
Druggable Family, this means that the target is considered druggable as per Finan et al ’s Druggable Genome pipeline.
I seem to find a discrepancy in terms of “Druggability Family” and DGIdb, both citing Finan et al. If you search for TSLP in OT, it does not belong to a Druggable Family in the Tractability section (thought it has Advanced Clinical ticked). However, DGIdb classify it as part of the Druggable Genome. I’ve attached two screenshots below. Thanks for your attention!
