Is all linkage presented in the 'evidence' folder direct evidence?

Technical Support
1

Dear all,
I am conducting an in-depth analysis of open-target data (I downloaded the raw data from the ftp). If I understand correctly, all the linkages (separated by data sources) in the evidence folder are direct linkages. The propagation to parental diseases were subsequently done to produce ‘indirect associations’ stored in the ‘association…Indirect’ folders, right?
Thanks!
Best,
Mengyi

2

This is correct mengysun.

3

Thanks for answering this! Might be dumb but where can I find the disease ontology used for the “propagation to parental diseases”?

4

There are no dumb questions here :wink:

Open Targets used the Experimental Factor Ontology (EFO) that feeds from other biomedical ontologies.

More info:

Browse EFO:
https://www.ebi.ac.uk/ols/ontologies/efo

EFO codebase and releases:

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