Ensembl id mismatch

Community Feedback
1

I recently downloaded the latest tractability dataset from the FTP site (dated 15/02/2023), having used previous versions of this file, and I noticed that in this newer version there appear to be a few errors in the Ensembl Id to gene symbol mappings.

Here is one example:

Sept 2022 version:

ENSG00000144029 MRPS5 P82675 RT05_HUMAN 28S ribosomal protein S5, mitochondrial (MRP-S5) (S5mt) (Mitochondrial small ribosomal subunit protein uS5m)

Open Targets Platform (id is still correct but has no tractability data on the platform)

Feb 2023 version:

ENSG00000289685 MRPS5 P82675 RT05_HUMAN 28S ribosomal protein S5, mitochondrial (MRP-S5) (S5mt) (Mitochondrial small ribosomal subunit protein uS5m)

(Open Targets Platform) (novel protein, has the tractability data)

I also have a list of around 40 other suspect Ensembl ids that have gone missing between versions, but I haven’t manually checked them all.

2

Hi! Welcome to the OpenTarget community forum. You are right, this behaviour is indeed unexpected and incorrect. This issue is being resolved in the upcoming Platform release expected within a few weeks. Please keep reporting inconsistencies or other issues you may find.

Best,
Daniel

3

That’s good to hear, thank you. I’ll keep an eye out for the new release.