21.09 Platform Release now live!

We have just released the latest data update to the Open Targets Platform — 21.09.

Key highlights for this release:

  • This release integrates tractability data for Proteolysis Targeting Chimeras (PROTACs), following the recent Open Targets publication of a new framework to assess the ‘PROTACtability’ of human proteins;

  • We have also integrated genetic constraint data from gnomAD, as well as new data on chemical probes from Probes&Drugs;

  • Finally, we have a number of data updates, including EFO 3.34.0, ChEMBL 29, and Mouse Genome Informatics.

This release integrates 11,071,233 evidence strings to build 10,102,184 target-disease associations between 18,663 diseases and 60,636 targets from the following 21 public resources:

Additionally, the Platform now allows users to explore data on 12,594 drugs.

For more details, read the 21.09 release blog post.

Hello Team – Thank you for the 21.09 release yesterday.

Is there a plan to release a “beta” or “testing” version earlier for future releases? The change yesterday broke one of our systems when the graphQL endpoints changed.’

It would be great to be able to test against the new release so we can help you find bugs, and it would give us time to make sure we’re able to switch to your new API at the same time.



Hello @Philip_Cheung! :wave:

Welcome to the Open Targets Community! :tada:

At the moment, we do not have a public beta release prior to our production release. However, this is something that may change in the future as we build out our new release process.

In the meantime, I would recommend that you adjust your internal system and utilise our data downloads. Our data downloads are versioned and provide the same insights. Our GraphQL API is optimised for a single query and was not built to support internal systems and dashboards. We are also still actively developing the next-gen Platform and so API fields are subject to change with no notice.

As you review the data from our GraphQL API or dataset downloads, you can report any bugs or data issues here in the Community or in our Platform GitHub issue tracker.

Also, we are in the process of building out our product roadmaps and that will help you plan for upcoming changes in later releases.

Thank you! :slight_smile: