# The latest release — 22.06 — is now live!

**URL:** https://community.opentargets.org/t/the-latest-release-22-06-is-now-live/675
**Category:** Releases
**Created:** [24 June 2022 11:07 UTC](https://community.opentargets.org/t/the-latest-release-22-06-is-now-live/675 "2022-06-24T11:07:28Z")
**Posts on this page:** 11
**Page:** 1

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### Author: ![hcornu](https://dub1.discourse-cdn.com/flex017/user_avatar/community.opentargets.org/hcornu/32/716_2.png) [@hcornu](https://community.opentargets.org/u/hcornu)
#### Post date: [24 June 2022 11:07 UTC](https://community.opentargets.org/t/the-latest-release-22-06-is-now-live/675/1 "2022-06-24T11:07:28Z")

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We have just released the latest data update to the Open Targets Platform — 22.06.

## Key highlights for this release:

- We have included five additional studies in our Gene Burden widget, incorporating evidence from several therapeutic areas
- The term “medical procedure” now exists in our ontology
- Users can now visualise subcellular locations of targets

This release integrates 14,455,104 evidence strings to build 7,247,865 target-disease associations between 23,074 diseases and 61,524 targets from the following 22 public resources:

- 1,541,903 genetic evidence from [European Variation Archive (EVA)](http://www.ebi.ac.uk/eva/)
- 694,214 genetic evidence from [Open Targets Genetics Portal](https://genetics.opentargets.org/)
- 4,454 genetic evidence from [Gene2Phenotype](https://www.ebi.ac.uk/gene2phenotype)
- 40,446 genetic evidence from the[Genomics England PanelApp](https://bioinfo.extge.co.uk/crowdsourcing/PanelApp/)
- 1,966 genetic evidence from [ClinGen](https://search.clinicalgenome.org/kb/gene-validity/)
- 8,506 genetic evidence from Orphanet
- 27,162 genetic evidence from Gene burden
- 7,727 genetic evidence from [UniProt Literature](https://www.uniprot.org/)
- 11,907 somatic evidence from [European Variation Archive (EVA)](http://www.ebi.ac.uk/eva/)
- 3,299 somatic evidence from[intOGen](https://www.intogen.org/)
- 74,345 somatic evidence from the[Cancer Gene Census](http://cancer.sanger.ac.uk/census/)
- 50,454 somatic evidence from [Uniprot](http://www.uniprot.org/)
- 596,593 drug evidence from [ChEMBL](https://www.ebi.ac.uk/chembl/)
- 231,165 expression evidence from [Expression Atlas](https://www.ebi.ac.uk/gxa/home)
- 10,345 affected pathway evidence from [Reactome](https://reactome.org/)
- 72,316 affected pathway evidence from [SLAPenrich](https://saezlab.github.io/SLAPenrich/)
- 378 affected pathway evidence from [PROGENy](https://saezlab.github.io/progeny/)
- 389 systems biology evidence from [SysBio](https://saezlab.github.io/progeny/)
- 1,966 somatic evidence from the [Cancer Genome Interpreter](https://www.cancergenomeinterpreter.org/home)
- 1,846 CRISPR-Cas9 (Cancer Cell Lines) evidence from[Behan et al. 2019](https://europepmc.org/abstract/MED/30971826)
- 1,157,536 mouse model evidence from [IMPC](https://www.mousephenotype.org/)
- 9,916,855 scientific literature evidence from co-occurence mining in [Europe PMC](https://europepmc.org/)

Additionally, the Platform now allows users to explore data on 12,854 drugs.

For more details, read[the 22.06 release blog post](https://blog.opentargets.org/open-targets-platform-22-06-release/).

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### Author: ![jasperhyp](https://dub1.discourse-cdn.com/flex017/user_avatar/community.opentargets.org/jasperhyp/32/186_2.png) [@jasperhyp](https://community.opentargets.org/u/jasperhyp)
#### Post date: [24 June 2022 21:31 UTC](https://community.opentargets.org/t/the-latest-release-22-06-is-now-live/675/2 "2022-06-24T21:31:38Z")

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Hi Helena, the FTP & gutils link provided at OT data portal seems not accessible now. The latest version is still updated on May. Will it be on later?

EDIT: To elaborate, basically, I can’t access [404 Not Found (ebi.ac.uk)](http://ftp.ebi.ac.uk/pub/databases/opentargets/platform/22.06/output/etl/json).

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### Author: ![ochoa](https://dub1.discourse-cdn.com/flex017/user_avatar/community.opentargets.org/ochoa/32/189_2.png) [@ochoa](https://community.opentargets.org/u/ochoa)
#### Post date: [25 June 2022 10:34 UTC](https://community.opentargets.org/t/the-latest-release-22-06-is-now-live/675/3 "2022-06-25T10:34:22Z")

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Apologies, as we are experiencing some difficulties with the EBI FTP servers that we are trying to resolve. You can follow the issue here:

> <https://github.com/opentargets/issues/issues/2652>
>
> As \[reported by a user in community\](https://community.opentargets.org/t/the-lat…est-release-22-06-is-now-live/675/2), the 22.06 data is not yet available in the EBI FTP. 
> 
> \`\`\`
> ls /ebi/ftp/pub/databases/opentargets/platform
> ...
> drwxr-sr-x 6 otftpuser opent 4.0K Nov 24 2021 21.11
> drwxr-sr-x 7 otftpuser opent 4.0K Mar 2 02:05 22.02
> drwxrwsr-x 7 otftpuser opent 4.0K May 4 01:21 22.04
> lrwxrwxrwx 1 mbernal opent 5 May 5 04:59 latest -\> 22.04
> \`\`\`

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### Author: ![jasperhyp](https://dub1.discourse-cdn.com/flex017/user_avatar/community.opentargets.org/jasperhyp/32/186_2.png) [@jasperhyp](https://community.opentargets.org/u/jasperhyp)
#### Post date: [26 June 2022 01:21 UTC](https://community.opentargets.org/t/the-latest-release-22-06-is-now-live/675/4 "2022-06-26T01:21:34Z")

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Thanks a lot for your prompt response! I noticed that it has been resolved.

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### Author: ![roman-hillje](https://dub1.discourse-cdn.com/flex017/user_avatar/community.opentargets.org/roman-hillje/32/192_2.png) [@roman-hillje](https://community.opentargets.org/u/roman-hillje)
#### Post date: [29 June 2022 08:41 UTC](https://community.opentargets.org/t/the-latest-release-22-06-is-now-live/675/5 "2022-06-29T08:41:19Z")

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Hi! Which state of the frontend have you deployed? I don’t see a release tag as there normally is: [Tags · opentargets/platform-app · GitHub](https://github.com/opentargets/platform-app/tags)

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### Author: ![carcruz](https://dub1.discourse-cdn.com/flex017/user_avatar/community.opentargets.org/carcruz/32/276_2.png) [@carcruz](https://community.opentargets.org/u/carcruz)
#### Post date: [30 June 2022 08:46 UTC](https://community.opentargets.org/t/the-latest-release-22-06-is-now-live/675/6 "2022-06-30T08:46:29Z")

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Hello Roman!

For the latest release of the UI and the followings, we are using the OT-UI-APPS repository.  
[GitHub - opentargets/ot-ui-apps](https://github.com/opentargets/ot-ui-apps) We are working on enforcing the documentation, but basically, this repo will replace platform-app and genetics-app.

You can read about why we are doing this change here: [Next steps in our web applications' architecture](https://blog.opentargets.org/next-steps-in-our-frontend-architecture-monorepo/)

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### Author: ![roman-hillje](https://dub1.discourse-cdn.com/flex017/user_avatar/community.opentargets.org/roman-hillje/32/192_2.png) [@roman-hillje](https://community.opentargets.org/u/roman-hillje)
#### Post date: [30 June 2022 09:23 UTC](https://community.opentargets.org/t/the-latest-release-22-06-is-now-live/675/7 "2022-06-30T09:23:39Z")

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Hey @carcruz !

Thank you for the explanation. I didn’t realize the `ot-ui-apps` repo was already used in production but that certainly explains why there is no release tag in the `platform-app` repo. I’ll check out the new repo in more detail then.

Thanks again!  
Roman

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### Author: ![Anita](https://avatars.discourse-cdn.com/v4/letter/a/49beb7/32.png) [@Anita](https://community.opentargets.org/u/Anita)
#### Post date: [6 July 2023 15:31 UTC](https://community.opentargets.org/t/the-latest-release-22-06-is-now-live/675/8 "2023-07-06T15:31:54Z")

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Hi Helena, some questions on the statistics of 22.06. I saw the annotation of the Drugs came from ChEMBL, including different level clinical precedence.

1. Is it means 12,854 drugs with 596,593 ( \* 596,593 drug evidence from [ChEMBL](https://www.ebi.ac.uk/chembl/)) evidence all extracted from ChEMBL database?

2. Do these 12,854 drugs also include compounds haven’t been approved ?

Thanks~

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### Author: ![hcornu](https://dub1.discourse-cdn.com/flex017/user_avatar/community.opentargets.org/hcornu/32/716_2.png) [@hcornu](https://community.opentargets.org/u/hcornu)
#### Post date: [7 July 2023 08:43 UTC](https://community.opentargets.org/t/the-latest-release-22-06-is-now-live/675/9 "2023-07-07T08:43:56Z")

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Hi @Anita,

1. Yes, our drugs and drug evidence is extracted from the ChEMBL database (ChEMBL is the only source of evidence in the data type ‘Drugs’, but we do have additional annotation data e.g. from FAERS.)

2. The evidence extracted from ChEMBL includes approved drugs and clinical candidates

I hope this helps!

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### Author: ![Anita](https://avatars.discourse-cdn.com/v4/letter/a/49beb7/32.png) [@Anita](https://community.opentargets.org/u/Anita)
#### Post date: [11 July 2023 14:51 UTC](https://community.opentargets.org/t/the-latest-release-22-06-is-now-live/675/10 "2023-07-11T14:51:17Z")

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Thanks a lot, got it! 😄

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### Author: ![yasir](https://avatars.discourse-cdn.com/v4/letter/y/9f8e36/32.png) [@yasir](https://community.opentargets.org/u/yasir)
#### Post date: [22 January 2025 15:22 UTC](https://community.opentargets.org/t/the-latest-release-22-06-is-now-live/675/12 "2025-01-22T15:22:06Z")

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amazing stuff, thanks a lot.
