Thank you for this wonderful resource. Could you please specify what is the significance threshold in the PheWAS plots, and how it was obtained? It appears to be around 1.3e-5 but I could not find it in the documentation.
Thanks in advance!
Hi @Adil_Harroud, and welcome to the Open Targets Community!
Only traits with P-value < 0.005 are returned on the PheWAS plot. I’m not sure if this answers your question?
Thank you for your reply. On the PheWAS plots (example attached), there is a horizontal red line near 10-5 on the y axis (p-values). Does this red horizontal line represent a certain significance threshold for the PheWAS? If so, what is this significance threshold and how was it obtained? Alternatively, could you provide the number of traits tested for FinnGen + UKB + GWAS Catalog?