# Our Next-Generation Platform has been released! (21.04)
**URL:** https://community.opentargets.org/t/our-next-generation-platform-has-been-released-21-04/73
**Category:** Releases
**Tags:** ot-platform, release-notes
**Created:** [29 April 2021 15:26 UTC](https://community.opentargets.org/t/our-next-generation-platform-has-been-released-21-04/73 "2021-04-29T15:26:41Z")
**Posts on this page:** 3
**Page:** 1
### Author:  [@hcornu](https://community.opentargets.org/u/hcornu)
#### Post date: [29 April 2021 15:26 UTC](https://community.opentargets.org/t/our-next-generation-platform-has-been-released-21-04/73/1 "2021-04-29T15:26:41Z")
The release of our next-generation Open Targets Platform is timed with our latest data release, considerably increasing the number of target-disease associations.
We integrate 13,648,521 evidence strings to build 11,986,840 target-disease associations between 14,413 diseases and 29,293 targets from the following 20 public resources:
- 837,193 genetic evidence from[European Variation Archive (EVA)](http://www.ebi.ac.uk/eva/)
- 388,324 genetic evidence from[Open Targets Genetics Portal](https://genetics.opentargets.org/)
- 2,550 genetic evidence from[Gene2Phenotype](https://www.ebi.ac.uk/gene2phenotype)
- 20,687 genetic evidence from the[Genomics England PanelApp](https://bioinfo.extge.co.uk/crowdsourcing/PanelApp/)
- 1,293 genetic evidence from[ClinGen](https://search.clinicalgenome.org/kb/gene-validity/)
- 182,800 genetic evidence from the[PheWAS catalog](https://phewascatalog.org/)
- 5,306 genetic evidence from[UniProt Literature](https://www.uniprot.org/)
- 11,187 somatic evidence from[European Variation Archive (EVA)](http://www.ebi.ac.uk/eva/)
- 3,292 somatic evidence from[intOGen](https://www.intogen.org/)
- 61,666 somatic evidence from the[Cancer Gene Census](http://cancer.sanger.ac.uk/census/)
- 33,465 somatic evidence from [Uniprot](http://www.uniprot.org/)
- 521,846 drug evidence from[ChEMBL](https://www.ebi.ac.uk/chembl/)
- 225,976 expression evidence from[Expression Atlas](https://www.ebi.ac.uk/gxa/home)
- 9,718 affected pathway evidence from[Reactome](https://reactome.org/)
- 78,057 affected pathway evidence from[SLAPenrich](https://saezlab.github.io/SLAPenrich/)
- 420 affected pathway evidence from[PROGENy](https://saezlab.github.io/progeny/)
- 423 systems biology evidence from[SysBio](https://saezlab.github.io/progeny/)
- 1,846 CRISPR-Cas9 (Cancer Cell Lines) evidence from[Behan et al. 2019](https://europepmc.org/abstract/MED/30971826)
- 711,386 mouse model evidence from[PhenoDigm](https://www.sanger.ac.uk/resources/databases/phenodigm)
- 10,551,086 scientific literature evidence from co-occurence mining in[Europe PMC](https://europepmc.org/)
### Key highlights for this release include:
- The new molecular interactions widget — featuring pairwise interaction data from Reactome, Intact, Signor, and String
- The inclusion of black box warnings and drug withdrawals through the latest ChEMBL release (ChEMBL 28)
- A new literature-mining strategy using natural language processing, in collaboration with Europe PMC.
For more details, read our [next-generation Platform release blog post](https://blog.opentargets.org/2021/04/29/next-gen-platform-released/).
You can also take a look at [the walkthrough on YouTube](https://www.youtube.com/watch?v=JO_DTtnMl4Y) and [the presentation on Slideshare](https://www.slideshare.net/HelenaCornu/the-next-generation-open-targets-platform-247333971).
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### Author:  [@community\_manager](https://community.opentargets.org/u/community_manager)
#### Post date: [29 April 2021 15:40 UTC](https://community.opentargets.org/t/our-next-generation-platform-has-been-released-21-04/73/2 "2021-04-29T15:40:47Z")
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### Author:  [@ahercules](https://community.opentargets.org/u/ahercules)
#### Post date: [11 June 2021 11:36 UTC](https://community.opentargets.org/t/our-next-generation-platform-has-been-released-21-04/73/3 "2021-06-11T11:36:48Z")