# Open Targets Genetics should support chrX variants

**URL:** <https://community.opentargets.org/t/open-targets-genetics-should-support-chrx-variants/1058>\
**Category:** Genetics feature requests\
**Tags:** data-updates\
**Created:** [26 April 2023 14:05 UTC](https://community.opentargets.org/t/open-targets-genetics-should-support-chrx-variants/1058 "2023-04-26T14:05:36Z")\
**Posts on this page:** 1\
**Page:** 1

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**Author:** ![jschwart37](https://dub1.discourse-cdn.com/flex017/user_avatar/community.opentargets.org/jschwart37/32/321_2.png) [@jschwart37](https://community.opentargets.org/u/jschwart37)\
**Post date:** [26 April 2023 14:05 UTC](https://community.opentargets.org/t/open-targets-genetics-should-support-chrx-variants/1058/1 "2023-04-26T14:05:36Z")

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As a user of the Open Targets Genetics, I would like to see associations for variants on the X chromosome.

Use case:  
We were investigating a variant ([Open Targets Genetics](https://genetics.opentargets.org/variant/X_12900169_G_A)) which is associated with SLE in a GWAS ([GWAS Catalog](https://www.ebi.ac.uk/gwas/studies/GCST011956)) that doesn’t include sumstats.

The variant is present in OT genetics, but no lead or tag variants are shown.

The code for fine-mapping currently has a note saying that it fails for chrX/Y:

> **[GitHub - opentargets/genetics-finemapping: Fine-mapping pipeline for Open...](https://github.com/opentargets/genetics-finemapping#notes)**
>
> Fine-mapping pipeline for Open Targets Genetics. Contribute to opentargets/genetics-finemapping development by creating an account on GitHub.

The same problem would be present for coloc, which relies on getting independent sumstats using GCTA-cojo in the same way as for fine-mapping.