# Large-scale rare variant burden testing in Parkinson's disease

**URL:** <https://community.opentargets.org/t/large-scale-rare-variant-burden-testing-in-parkinsons-disease/1280>\
**Category:** General\
**Tags:** genetics-portal\
**Created:** [14 November 2023 01:32 UTC](https://community.opentargets.org/t/large-scale-rare-variant-burden-testing-in-parkinsons-disease/1280 "2023-11-14T01:32:18Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![Shicheng\_Guo](https://dub1.discourse-cdn.com/flex017/user_avatar/community.opentargets.org/shicheng_guo/32/217_2.png) [@Shicheng\_Guo](https://community.opentargets.org/u/Shicheng_Guo)\
**Post date:** [14 November 2023 01:32 UTC](https://community.opentargets.org/t/large-scale-rare-variant-burden-testing-in-parkinsons-disease/1280/1 "2023-11-14T01:32:18Z")

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Dear Team,

I am wondering how OT team is handling single burden test association study? I find this paper is quite interesting, but just curious if such paper ( [Large-scale rare variant burden testing in Parkinson’s disease - PubMed](https://pubmed.ncbi.nlm.nih.gov/37348876/)) will be included to the opentarget platform?

> **[Large-scale rare variant burden testing in Parkinson's disease - PubMed](https://pubmed.ncbi.nlm.nih.gov/37348876/)**
>
> Parkinson's disease has a large heritable component and genome-wide association studies have identified over 90 variants with disease-associated common variants, providing deeper insights into the disease biology. However, there have not been...

Best,

Shicheng

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**Author:** ![ochoa](https://dub1.discourse-cdn.com/flex017/user_avatar/community.opentargets.org/ochoa/32/189_2.png) [@ochoa](https://community.opentargets.org/u/ochoa)\
**Post date:** [14 November 2023 09:37 UTC](https://community.opentargets.org/t/large-scale-rare-variant-burden-testing-in-parkinsons-disease/1280/2 "2023-11-14T09:37:35Z")

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We will include it in the backlog. Thank you @Shicheng_Guo!  
cc @irene