# Are the p value displayed in table of GWAS l2g table is the p value in original GWAS files?

**URL:** <https://community.opentargets.org/t/are-the-p-value-displayed-in-table-of-gwas-l2g-table-is-the-p-value-in-original-gwas-files/1570>\
**Category:** Community Feedback\
**Created:** [30 September 2024 14:16 UTC](https://community.opentargets.org/t/are-the-p-value-displayed-in-table-of-gwas-l2g-table-is-the-p-value-in-original-gwas-files/1570 "2024-09-30T14:16:51Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![Li\_Yujue](https://dub1.discourse-cdn.com/flex017/user_avatar/community.opentargets.org/li_yujue/32/679_2.png) [@Li\_Yujue](https://community.opentargets.org/u/Li_Yujue)\
**Post date:** [30 September 2024 14:16 UTC](https://community.opentargets.org/t/are-the-p-value-displayed-in-table-of-gwas-l2g-table-is-the-p-value-in-original-gwas-files/1570/1 "2024-09-30T14:16:51Z")

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For example, in BMI trait: **[Open Targets Genetics](https://genetics.opentargets.org/Study/NEALE2_21001_raw/associations)**, does the p-value in `Association Information` table display the p-values in GWAS summary statistics? Thank you!

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**Author:** ![Annalisa\_Buniello](https://dub1.discourse-cdn.com/flex017/user_avatar/community.opentargets.org/annalisa_buniello/32/426_2.png) [@Annalisa\_Buniello](https://community.opentargets.org/u/Annalisa_Buniello)\
**Post date:** [1 October 2024 09:43 UTC](https://community.opentargets.org/t/are-the-p-value-displayed-in-table-of-gwas-l2g-table-is-the-p-value-in-original-gwas-files/1570/2 "2024-10-01T09:43:45Z")

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Dear Li\_Yujue, welcome to our Community and thank you for your question.  
In the example reported by you (GWAS study with summary statistics), the value in the Association Information is the conditional pvalue on secondary signals as reported by [COJO](https://genetics-docs.opentargets.org/our-approach/assigning-traits-to-loci#fine-mapping-expansion). When a study does not have sumstats, that is the top-hit curated p-value as reported in the original publication.

I hope this helps!

Best wishes,  
Annalisa
