# Feature requests **URL:** https://community.opentargets.org/c/feature-requests/16.md [Latest](https://community.opentargets.org/latest.md) · [Categories](https://community.opentargets.org/categories.md) · [Tags](https://community.opentargets.org/tags.md) --- ## [About the Feature requests category](https://community.opentargets.org/t/about-the-feature-requests-category/39)
**Author:** [@community\_manager](https://community.opentargets.org/u/community_manager)\ **Replies:** 0
Please post here, with the relevant tags, if you would like to submit a suggestion to the team about how we can improve the Open Targets platforms. If the request you would like to make has already been posted, please l… --- ## [Incorporate predicted protein structures in tractability scores](https://community.opentargets.org/t/incorporate-predicted-protein-structures-in-tractability-scores/1073)
**Author:** [@eczech](https://community.opentargets.org/u/eczech)\ **Replies:** 0\ **Last updated:** [4 May 2023 18:10 UTC](https://community.opentargets.org/t/incorporate-predicted-protein-structures-in-tractability-scores/1073 "2023-05-04T18:10:23Z")
Hi, do you all have any plans/ideas on ways to incorporate new structure prediction models in the current tractability scoring system? I was curious if you’re aware of any leading efforts to this end via AlphaFold or Ros… --- ## [Enable evidence trend analysis (e.g. in ClinVar)](https://community.opentargets.org/t/enable-evidence-trend-analysis-e-g-in-clinvar/1235)
**Author:** [@eczech](https://community.opentargets.org/u/eczech)\ **Replies:** 4\ **Last updated:** [19 October 2023 17:09 UTC](https://community.opentargets.org/t/enable-evidence-trend-analysis-e-g-in-clinvar/1235 "2023-10-19T17:09:12Z")
It would be very helpful for us to know when records in ClinVar were first submitted. This is important for us because the timing of emerging evidence is something we attempt to account for frequently. I expect that th… --- ## [Does Open Targets have a table of drugs with a safety rating based on adverse events?](https://community.opentargets.org/t/does-open-targets-have-a-table-of-drugs-with-a-safety-rating-based-on-adverse-events/461)
**Author:** [@SirTarget](https://community.opentargets.org/u/SirTarget)\ **Replies:** 1\ **Last updated:** [17 February 2022 20:36 UTC](https://community.opentargets.org/t/does-open-targets-have-a-table-of-drugs-with-a-safety-rating-based-on-adverse-events/461 "2022-02-17T20:36:32Z")
Do you know if Open Targets is going to offer any downloads that can be quickly leveraged for deep learning algorithms? It would be great if Open Targets could offer a table of drugs with a safety rating based on their a… --- ## [Having a shared variant model between the Genetics Portal and the Platform](https://community.opentargets.org/t/having-a-shared-variant-model-between-the-genetics-portal-and-the-platform/1053)
**Author:** [@dsuveges](https://community.opentargets.org/u/dsuveges)\ **Replies:** 0\ **Last updated:** [20 April 2023 13:49 UTC](https://community.opentargets.org/t/having-a-shared-variant-model-between-the-genetics-portal-and-the-platform/1053 "2023-04-20T13:49:34Z")
On the Platform, a growing number of evidence sources have some sort of variant information, however at this point, variant information is just an annotation. Having a variant entity would be highly advantageous as it wo… --- ## [Incorporation of predicted protein structures in tractability scores in the Open Targets Platform](https://community.opentargets.org/t/incorporation-of-predicted-protein-structures-in-tractability-scores-in-the-open-targets-platform/618)
**Author:** [@hcornu](https://community.opentargets.org/u/hcornu)\ **Replies:** 0\ **Last updated:** [23 May 2022 16:28 UTC](https://community.opentargets.org/t/incorporation-of-predicted-protein-structures-in-tractability-scores-in-the-open-targets-platform/618 "2022-05-23T16:28:40Z")
A recent question posed in our GitHub issue tracker (see Issue #1886), was whether the Open Targets team had any plans to incorporate new structure prediction models in the current tractability scoring system, via AlphaF… --- ## [Proposal: Adding genome-wide genetic correlation matrix to OpenTargets?](https://community.opentargets.org/t/proposal-adding-genome-wide-genetic-correlation-matrix-to-opentargets/1969)
**Author:** [@shastvx1](https://community.opentargets.org/u/shastvx1)\ **Replies:** 2\ **Last updated:** [13 January 2026 19:06 UTC](https://community.opentargets.org/t/proposal-adding-genome-wide-genetic-correlation-matrix-to-opentargets/1969 "2026-01-13T19:06:38Z")
Background The OpenTargets Platform currently provides powerful tools for understanding locus-level relationships between studies. These identify shared causal variants at specific genomic loci. However, there is current… --- ## [Adding Jackson Lab Mouse Data](https://community.opentargets.org/t/adding-jackson-lab-mouse-data/1244)
**Author:** [@RMehovic](https://community.opentargets.org/u/RMehovic)\ **Replies:** 4\ **Last updated:** [17 October 2023 09:42 UTC](https://community.opentargets.org/t/adding-jackson-lab-mouse-data/1244 "2023-10-17T09:42:59Z")
Hi, Are there any plans to incorporate mouse model information from Jackson lab? https://www.informatics.jax.org/ --- ## [Inferring direction of therapeutic effect implied by coding genetic evidence](https://community.opentargets.org/t/inferring-direction-of-therapeutic-effect-implied-by-coding-genetic-evidence/1225)
**Author:** [@eczech](https://community.opentargets.org/u/eczech)\ **Replies:** 5\ **Last updated:** [23 October 2023 09:23 UTC](https://community.opentargets.org/t/inferring-direction-of-therapeutic-effect-implied-by-coding-genetic-evidence/1225 "2023-10-23T09:23:15Z")
How would you all suggest Open Targets be used to infer whether or not a statistical association between a gene and a disease suggests an opportunity for an agonistic or antagonistic therapeutic? It seems to me that bet… --- ## [Clinical trial source link](https://community.opentargets.org/t/clinical-trial-source-link/1106)
**Author:** [@Ellen\_McDonagh](https://community.opentargets.org/u/Ellen_McDonagh)\ **Replies:** 1\ **Last updated:** [15 June 2023 14:13 UTC](https://community.opentargets.org/t/clinical-trial-source-link/1106 "2023-06-15T14:13:52Z")
From the clinical precedence table, it would be nice to be redirected to the specific clinical trial page instead of the general clinical trials.gov example: https://partner-platform.opentargets.org/drug/CHEMBL4297240 … --- ## [Druggability for given target](https://community.opentargets.org/t/druggability-for-given-target/614)
**Author:** [@Shicheng\_Guo](https://community.opentargets.org/u/Shicheng_Guo)\ **Replies:** 3\ **Last updated:** [27 May 2022 19:19 UTC](https://community.opentargets.org/t/druggability-for-given-target/614 "2022-05-27T19:19:39Z")
Dear Team, EBI-EBML has a measurement on druggability for given target. I am wondering whether this metric has been implemented in OT platform? Druggability is a term used in drug discovery to describe a biological tar… --- ## [New feature for Platform Drug Page: drug targeted pathways](https://community.opentargets.org/t/new-feature-for-platform-drug-page-drug-targeted-pathways/779)
**Author:** [@Margaret\_Linan](https://community.opentargets.org/u/Margaret_Linan)\ **Replies:** 0\ **Last updated:** [28 September 2022 23:14 UTC](https://community.opentargets.org/t/new-feature-for-platform-drug-page-drug-targeted-pathways/779 "2022-09-28T23:14:03Z")
Dear Team, I am the founder and biocurator at the Retrosynthesis AI Platform, and I have noticed that popular databases such as Reactome, PharmGKB, DrugBank, and Comparative Toxicogenomics Database lack a tremendous num… --- ## [Batch query for biomarker prioritization](https://community.opentargets.org/t/batch-query-for-biomarker-prioritization/98)
**Author:** [@cbattaglia](https://community.opentargets.org/u/cbattaglia)\ **Replies:** 1\ **Last updated:** [13 May 2021 16:47 UTC](https://community.opentargets.org/t/batch-query-for-biomarker-prioritization/98 "2021-05-13T16:47:08Z")
Hi, in the previous version of open target it could run a batch query with 200 genes which was a great feature for biomarker prioritization. Is it still possible with the new version? Thank you Cristina --- ## [Format of genomic data in the ClinVar widget](https://community.opentargets.org/t/format-of-genomic-data-in-the-clinvar-widget/489)
**Author:** [@wintercl](https://community.opentargets.org/u/wintercl)\ **Replies:** 6\ **Last updated:** [28 April 2022 14:24 UTC](https://community.opentargets.org/t/format-of-genomic-data-in-the-clinvar-widget/489 "2022-04-28T14:24:00Z")
Good day Open Targets! I am seeing that ClinVar widget genomic data has been converted from HGVS to some other format rather than HGVS format. The display of large insertions in columns are problematic in this kind of f… --- ## [Are there plans to integrate scRNA-seq, HCA dataset in the Open Targets Platform?](https://community.opentargets.org/t/are-there-plans-to-integrate-scrna-seq-hca-dataset-in-the-open-targets-platform/660)
**Author:** [@Shicheng\_Guo](https://community.opentargets.org/u/Shicheng_Guo)\ **Replies:** 1\ **Last updated:** [13 June 2022 09:12 UTC](https://community.opentargets.org/t/are-there-plans-to-integrate-scrna-seq-hca-dataset-in-the-open-targets-platform/660 "2022-06-13T09:12:32Z")
I am wondering is there any plan to engage scRNA-seq into the platform? for example, HCA dataset Thanks. Shicheng --- ## [Do you plan to integrate Genebass into the Open Targets informatics tools?](https://community.opentargets.org/t/do-you-plan-to-integrate-genebass-into-the-open-targets-informatics-tools/611)
**Author:** [@Shicheng\_Guo](https://community.opentargets.org/u/Shicheng_Guo)\ **Replies:** 1\ **Last updated:** [24 June 2022 11:28 UTC](https://community.opentargets.org/t/do-you-plan-to-integrate-genebass-into-the-open-targets-informatics-tools/611 "2022-06-24T11:28:48Z")
Dear Team, I thought genebass gene-based association has been integrated to opentargets, but it looks not. I am wondering is there any plan to integrated gene-based analysis result into the platform, including UKB and F… --- ## [Field "targetFromSource" in JSONs from EBI FTP data downloads](https://community.opentargets.org/t/field-targetfromsource-in-jsons-from-ebi-ftp-data-downloads/902)
**Author:** [@pviktrp](https://community.opentargets.org/u/pviktrp)\ **Replies:** 2\ **Last updated:** [20 December 2022 06:32 UTC](https://community.opentargets.org/t/field-targetfromsource-in-jsons-from-ebi-ftp-data-downloads/902 "2022-12-20T06:32:44Z")
Hello! I used Open Targets v21.04 in my research. In particular I was interested in the evidence derived from Europe PMC. There was a field in JSONs available for downloading (Index of /pub/databases/opentargets/platfo… --- ## [Gene-disease association score from disgenet](https://community.opentargets.org/t/gene-disease-association-score-from-disgenet/616)
**Author:** [@Shicheng\_Guo](https://community.opentargets.org/u/Shicheng_Guo)\ **Replies:** 1\ **Last updated:** [24 May 2022 13:20 UTC](https://community.opentargets.org/t/gene-disease-association-score-from-disgenet/616 "2022-05-24T13:20:57Z")
Dear Team, I’d like to recommend introducing gene-disease association score from disgenet to OT platform. Looking forward to receiving some feedback from your internal discussion. https://www.disgenet.org/dbinfo Thank… --- ## [Open Cravat App Request](https://community.opentargets.org/t/open-cravat-app-request/402)
**Author:** [@adamwest](https://community.opentargets.org/u/adamwest)\ **Replies:** 1\ **Last updated:** [10 November 2021 12:45 UTC](https://community.opentargets.org/t/open-cravat-app-request/402 "2021-11-10T12:45:16Z")
Could you create an app for Open Cravat? It would be immensely useful. --- ## [Getting signs of GWAS effects relative to major alleles instead of alt alleles](https://community.opentargets.org/t/getting-signs-of-gwas-effects-relative-to-major-alleles-instead-of-alt-alleles/1224)
**Author:** [@eczech](https://community.opentargets.org/u/eczech)\ **Replies:** 5\ **Last updated:** [19 October 2023 18:51 UTC](https://community.opentargets.org/t/getting-signs-of-gwas-effects-relative-to-major-alleles-instead-of-alt-alleles/1224 "2023-10-19T18:51:32Z")
Have there been past discussions on how to get GWAS effect signs for major alleles using data already in Open Targets? I see https://genetics-docs.opentargets.org/faqs#what-is-the-alternative-allele-why-not-use-the-mino… --- ## [Do you plan on adding filtering for Human based studies?](https://community.opentargets.org/t/do-you-plan-on-adding-filtering-for-human-based-studies/1813)
**Author:** [@je71xusa](https://community.opentargets.org/u/je71xusa)\ **Replies:** 1\ **Last updated:** [19 June 2025 13:39 UTC](https://community.opentargets.org/t/do-you-plan-on-adding-filtering-for-human-based-studies/1813 "2025-06-19T13:39:33Z")
Hello Open Targets Team! I like the possibility to filter for scores based on specific sources like the Europe PMC. Do you plan to incorparate more categories such as scores based on sources with human data, mouse data,… --- ## [GBMI summary statistics is included or not?](https://community.opentargets.org/t/gbmi-summary-statistics-is-included-or-not/570)
**Author:** [@Shicheng\_Guo](https://community.opentargets.org/u/Shicheng_Guo)\ **Replies:** 2\ **Last updated:** [16 October 2023 20:42 UTC](https://community.opentargets.org/t/gbmi-summary-statistics-is-included-or-not/570 "2023-10-16T20:42:07Z")
Dear Team, I am wondering whether GBMI summary statistics is included in the platform or not? http://results.globalbiobankmeta.org/ Thanks. Shicheng --- ## [Availability of Newly Released Heart Failure GWAS in Open Targets](https://community.opentargets.org/t/availability-of-newly-released-heart-failure-gwas-in-open-targets/1948)
**Author:** [@dbfk2000](https://community.opentargets.org/u/dbfk2000)\ **Replies:** 4\ **Last updated:** [17 December 2025 20:35 UTC](https://community.opentargets.org/t/availability-of-newly-released-heart-failure-gwas-in-open-targets/1948 "2025-12-17T20:35:25Z")
Dear Open Targets Team, Hi, I always enjoy using your platform to investigate new findings. Recently, a new GWAS dataset for heart failure has been released. I want to use the new data to see the colocalization with o… --- ## [Is there a plan to integrate MedlinePlus in the OT Platform?](https://community.opentargets.org/t/is-there-a-plan-to-integrate-medlineplus-in-the-ot-platform/676)
**Author:** [@Shicheng\_Guo](https://community.opentargets.org/u/Shicheng_Guo)\ **Replies:** 1\ **Last updated:** [20 July 2022 14:41 UTC](https://community.opentargets.org/t/is-there-a-plan-to-integrate-medlineplus-in-the-ot-platform/676 "2022-07-20T14:41:55Z")
Dear Team, I am wondering is there any plan to engage MedlinePlus ? Thanks. Shicheng --- ## [Metadata hashID for downloaded files via WGET](https://community.opentargets.org/t/metadata-hashid-for-downloaded-files-via-wget/1409)
**Author:** [@koryclick](https://community.opentargets.org/u/koryclick)\ **Replies:** 0\ **Last updated:** [23 April 2024 11:56 UTC](https://community.opentargets.org/t/metadata-hashid-for-downloaded-files-via-wget/1409 "2024-04-23T11:56:24Z")
Hello again OT team! I was looking in the data structure of the json files if is it any metadata column/child associated to a hashid for that table. It would be great to keep traceability of our analysis (reproducible … --- ## [Fine-mapping using the GCTA-COJO software](https://community.opentargets.org/t/fine-mapping-using-the-gcta-cojo-software/1120)
**Author:** [@deniseo](https://community.opentargets.org/u/deniseo)\ **Replies:** 2\ **Last updated:** [22 June 2023 13:43 UTC](https://community.opentargets.org/t/fine-mapping-using-the-gcta-cojo-software/1120 "2023-06-22T13:43:04Z")
Hi and thank you for the development of this platform. I would like to implement the COJO pipeline on my data as performed here by Open Targets. I am aware of the documentation page and the GitHub repository, however the… --- ## [On the Platform, is it possible to sort or filter Bibliography results by year of publication?](https://community.opentargets.org/t/on-the-platform-is-it-possible-to-sort-or-filter-bibliography-results-by-year-of-publication/551)
**Author:** [@Ellen\_McDonagh](https://community.opentargets.org/u/Ellen_McDonagh)\ **Replies:** 3\ **Last updated:** [20 March 2024 12:59 UTC](https://community.opentargets.org/t/on-the-platform-is-it-possible-to-sort-or-filter-bibliography-results-by-year-of-publication/551 "2024-03-20T12:59:08Z")
This would be really useful functionality --- ## [Suggested drug for inclusion](https://community.opentargets.org/t/suggested-drug-for-inclusion/511)
**Author:** [@SirTarget](https://community.opentargets.org/u/SirTarget)\ **Replies:** 1\ **Last updated:** [21 March 2022 20:03 UTC](https://community.opentargets.org/t/suggested-drug-for-inclusion/511 "2022-03-21T20:03:18Z")
I’d like to suggest 4-(2-Chlorophenyl)-8-(2-Hydroxyethyl)-6-Methylpyrrolo\[3,4-E\]indole-1,3(2h,6h)-Dione (CHEMBL ID: 11602832) for inclusion. It’s already indirectly cross-referenced to DrugBank (DB07257) as an associate…