# Community Feedback **URL:** https://community.opentargets.org/c/community-feedback/33.md?page=1 [Latest](https://community.opentargets.org/latest.md) · [Categories](https://community.opentargets.org/categories.md) · [Tags](https://community.opentargets.org/tags.md) **Page:** 2 --- ## [Incoherency between score in a disease page and a gene page](https://community.opentargets.org/t/incoherency-between-score-in-a-disease-page-and-a-gene-page/1676)
**Author:** [@Aner\_Ottolenghi](https://community.opentargets.org/u/Aner_Ottolenghi)\ **Replies:** 4\ **Last updated:** [24 February 2025 14:12 UTC](https://community.opentargets.org/t/incoherency-between-score-in-a-disease-page-and-a-gene-page/1676 "2025-02-24T14:12:49Z")
When I was looking on the association of ITGA4 and autoimmune disease, I get a different score depending on whether I’m looking in the gene page or disease page --- ## [Where to find half-life data in OT platform?](https://community.opentargets.org/t/where-to-find-half-life-data-in-ot-platform/1675)
**Author:** [@Shicheng\_Guo](https://community.opentargets.org/u/Shicheng_Guo)\ **Replies:** 1\ **Last updated:** [24 February 2025 09:29 UTC](https://community.opentargets.org/t/where-to-find-half-life-data-in-ot-platform/1675 "2025-02-24T09:29:49Z")
Dear Team, Where I can find Half-life data just like the figure showed below? Thanks, --- ## [MaxIndicationPhase being -1 in clinical trials dataset in OpenTargets Platform- what does it mean?](https://community.opentargets.org/t/maxindicationphase-being-1-in-clinical-trials-dataset-in-opentargets-platform-what-does-it-mean/1674)
**Author:** [@piotrkan](https://community.opentargets.org/u/piotrkan)\ **Replies:** 1\ **Last updated:** [21 February 2025 15:54 UTC](https://community.opentargets.org/t/maxindicationphase-being-1-in-clinical-trials-dataset-in-opentargets-platform-what-does-it-mean/1674 "2025-02-21T15:54:49Z")
Hi, my first post here so apologies if it’s not the right place to post! I played with OpenTargets data that I found here, specifically Drug - Indications dataset in a parquet format: Open Targets Platform I find the d… --- ## [Is the graphql api down?](https://community.opentargets.org/t/is-the-graphql-api-down/1641)
**Author:** [@Ani](https://community.opentargets.org/u/Ani)\ **Replies:** 4\ **Last updated:** [18 February 2025 10:56 UTC](https://community.opentargets.org/t/is-the-graphql-api-down/1641 "2025-02-18T10:56:30Z")
Im not able to query using the graphql API. query DrugInsightsByCompany { drug(chemblId: "CHEMBL25") { # Replace with the ChEMBL ID from Step 1 id name drugType isApproved maximumClinicalTrialPhas… --- ## [Indication duplication resulting from capitalization](https://community.opentargets.org/t/indication-duplication-resulting-from-capitalization/1667)
**Author:** [@janschultink](https://community.opentargets.org/u/janschultink)\ **Replies:** 1\ **Last updated:** [18 February 2025 10:40 UTC](https://community.opentargets.org/t/indication-duplication-resulting-from-capitalization/1667 "2025-02-18T10:40:42Z")
There are a number of duplicates in the indication DB based on capitalization. Example: “dementia” and “Dementia”. Checking the profile of the second one produces an error when trying to generate the indication tree. I … --- ## [502 Bad gateway error when calling the API](https://community.opentargets.org/t/502-bad-gateway-error-when-calling-the-api/1015)
**Author:** [@Lucie\_Gattepaille](https://community.opentargets.org/u/Lucie_Gattepaille)\ **Replies:** 8\ **Last updated:** [29 January 2025 09:36 UTC](https://community.opentargets.org/t/502-bad-gateway-error-when-calling-the-api/1015 "2025-01-29T09:36:26Z")
Hello community! I am trying the retrieve pages with disease → targets associations. Some pages work, then every time, after a while, I get a 502 Error Bad Gateway. I am cautious of not getting my IP blocked, so I prefe… --- ## [No ontology for aging?](https://community.opentargets.org/t/no-ontology-for-aging/1620)
**Author:** [@SolomonLalala](https://community.opentargets.org/u/SolomonLalala)\ **Replies:** 1\ **Last updated:** [10 December 2024 09:10 UTC](https://community.opentargets.org/t/no-ontology-for-aging/1620 "2024-12-10T09:10:11Z")
Hello, when I looked at aging profile, I did not find the ontology for aging. Does it not have an ontology or something is wrong? Thank you --- ## [Are the p value displayed in table of GWAS l2g table is the p value in original GWAS files?](https://community.opentargets.org/t/are-the-p-value-displayed-in-table-of-gwas-l2g-table-is-the-p-value-in-original-gwas-files/1570)
**Author:** [@Li\_Yujue](https://community.opentargets.org/u/Li_Yujue)\ **Replies:** 1\ **Last updated:** [1 October 2024 09:43 UTC](https://community.opentargets.org/t/are-the-p-value-displayed-in-table-of-gwas-l2g-table-is-the-p-value-in-original-gwas-files/1570 "2024-10-01T09:43:45Z")
For example, in BMI trait: Open Targets Genetics, does the p-value in Association Information table display the p-values in GWAS summary statistics? Thank you! --- ## [Gene burden source mismatch](https://community.opentargets.org/t/gene-burden-source-mismatch/1559)
**Author:** [@kimjonggeolj](https://community.opentargets.org/u/kimjonggeolj)\ **Replies:** 1\ **Last updated:** [30 September 2024 13:02 UTC](https://community.opentargets.org/t/gene-burden-source-mismatch/1559 "2024-09-30T13:02:10Z")
Hello Open Targets team, I noticed that on the Parkinson’s disease page, several gene burden evidence are being attributed to the wrong manuscript. Here, B3GNT3 gene burden evidence points toward Riveros-Mckay et al… --- ## [Setup OpenTarget Platform on Local machine](https://community.opentargets.org/t/setup-opentarget-platform-on-local-machine/1567)
**Author:** [@shailesh](https://community.opentargets.org/u/shailesh)\ **Replies:** 2\ **Last updated:** [30 September 2024 05:30 UTC](https://community.opentargets.org/t/setup-opentarget-platform-on-local-machine/1567 "2024-09-30T05:30:43Z")
Hi, While setting up OpenTraget locally, I am encountering an issue with the ot-es container in my setup. When I attempt to run the application, the container is marked as unhealthy, and I receive the following error: … --- ## ['Target Distribution' and 'Target Specificity'](https://community.opentargets.org/t/target-distribution-and-target-specificity/1534)
**Author:** [@Bob\_Zimmermann](https://community.opentargets.org/u/Bob_Zimmermann)\ **Replies:** 2\ **Last updated:** [26 August 2024 17:56 UTC](https://community.opentargets.org/t/target-distribution-and-target-specificity/1534 "2024-08-26T17:56:20Z")
Hello everyone, I am trying to better understand the target distribution and target specificity scores and I came across a few cases that confused me. The documentation states that the tissue distribution for a gene sho… --- ## [What's the plan to integrate DepMap?](https://community.opentargets.org/t/whats-the-plan-to-integrate-depmap/579)
**Author:** [@Shicheng\_Guo](https://community.opentargets.org/u/Shicheng_Guo)\ **Replies:** 2\ **Last updated:** [20 August 2024 16:55 UTC](https://community.opentargets.org/t/whats-the-plan-to-integrate-depmap/579 "2024-08-20T16:55:02Z")
Dear Team, What’s the plan to integrate DepMap into the platform? Thanks Shicheng --- ## [Drug-indication/Clinical precedence pairs on Open Targets](https://community.opentargets.org/t/drug-indication-clinical-precedence-pairs-on-open-targets/1525)
**Author:** [@Uzor](https://community.opentargets.org/u/Uzor)\ **Replies:** 1\ **Last updated:** [13 August 2024 10:42 UTC](https://community.opentargets.org/t/drug-indication-clinical-precedence-pairs-on-open-targets/1525 "2024-08-13T10:42:13Z")
Dear Open Targets team, I need a bit of clarification regarding how the drug-indication/clinical precedence pairs are curated on the platform. The Open Targets documentation states that clinical precedence for drugs are … --- ## [Is it any essential difference in the "targets" dataset, between synonyms and nameSynonyms?](https://community.opentargets.org/t/is-it-any-essential-difference-in-the-targets-dataset-between-synonyms-and-namesynonyms/1486)
**Author:** [@koryclick](https://community.opentargets.org/u/koryclick)\ **Replies:** 1\ **Last updated:** [25 July 2024 10:32 UTC](https://community.opentargets.org/t/is-it-any-essential-difference-in-the-targets-dataset-between-synonyms-and-namesynonyms/1486 "2024-07-25T10:32:13Z")
I am parsing the data of the json and I wonder what key to use for my query, synonyms or nameSynonyms: I found that at least for the first names, the labels are essentially the same. And the name is not very descript… --- ## [Target-disease and disease id - disease name Bugs report](https://community.opentargets.org/t/target-disease-and-disease-id-disease-name-bugs-report/1489)
**Author:** [@Vittorio\_lembo](https://community.opentargets.org/u/Vittorio_lembo)\ **Replies:** 3\ **Last updated:** [24 July 2024 14:24 UTC](https://community.opentargets.org/t/target-disease-and-disease-id-disease-name-bugs-report/1489 "2024-07-24T14:24:10Z")
Hi everyone, I want to report two ‘bugs’ I found while running scripts to query target-disease associations. The first one regards the protein KDM4C (lysine demethylase 4C, UniProt ID: Q9H3R0). While running a query (… --- ## [Found 3 papers tagged with melanoma that are about methylation](https://community.opentargets.org/t/found-3-papers-tagged-with-melanoma-that-are-about-methylation/1472)
**Author:** [@Su\_Mo](https://community.opentargets.org/u/Su_Mo)\ **Replies:** 5\ **Last updated:** [17 July 2024 01:52 UTC](https://community.opentargets.org/t/found-3-papers-tagged-with-melanoma-that-are-about-methylation/1472 "2024-07-17T01:52:23Z")
This issue is similar to my previous issue about gonorrhea and gastric cancer. I found 3 papers that I believe are tagged with “melanoma” in OpenTargets but are really about “methylation”, is that possible? I am not sur… --- ## [Deploying Open Targets Genetics using Terraform](https://community.opentargets.org/t/deploying-open-targets-genetics-using-terraform/1462)
**Author:** [@manikantan.ravikumar](https://community.opentargets.org/u/manikantan.ravikumar)\ **Replies:** 1\ **Last updated:** [26 June 2024 08:56 UTC](https://community.opentargets.org/t/deploying-open-targets-genetics-using-terraform/1462 "2024-06-26T08:56:29Z")
I am trying to develop the open target genetics cloud static website using the GitHub - opentargets/terraform-google-genetics-portal: Repo for Genetics Portal deployment link but unable to create it, got stucked at error … --- ## [Potential error in phenotype mapping](https://community.opentargets.org/t/potential-error-in-phenotype-mapping/1387)
**Author:** [@Jacob\_Degner](https://community.opentargets.org/u/Jacob_Degner)\ **Replies:** 3\ **Last updated:** [19 June 2024 15:10 UTC](https://community.opentargets.org/t/potential-error-in-phenotype-mapping/1387 "2024-06-19T15:10:33Z")
This page suggests a link between chronic myeloproliforative disorders and IGF1. Further inspection suggests there is no link to myeloproliforative disorders. (https://platform.opentargets.org/evidence/ENSG00000017427/EF… --- ## [Remove all category based analysis of genebass from OpenTargets platform](https://community.opentargets.org/t/remove-all-category-based-analysis-of-genebass-from-opentargets-platform/1393)
**Author:** [@Shicheng\_Guo](https://community.opentargets.org/u/Shicheng_Guo)\ **Replies:** 4\ **Last updated:** [19 June 2024 15:08 UTC](https://community.opentargets.org/t/remove-all-category-based-analysis-of-genebass-from-opentargets-platform/1393 "2024-06-19T15:08:40Z")
Dear Team, I would like to propose removing all category-based analysis of genebass from the OpenTargets platform. Upon further examination, I have concerns regarding the reliability and accuracy of these results, as ma… --- ## [Coloc results using GCST003043-5 missing from certain genes now](https://community.opentargets.org/t/coloc-results-using-gcst003043-5-missing-from-certain-genes-now/1441)
**Author:** [@mturchin20](https://community.opentargets.org/u/mturchin20)\ **Replies:** 1\ **Last updated:** [6 June 2024 15:44 UTC](https://community.opentargets.org/t/coloc-results-using-gcst003043-5-missing-from-certain-genes-now/1441 "2024-06-06T15:44:50Z")
Hello, I believe there are some colocalization results missing from some genes using GCST003043/GCST003044/GCST003045. For example, I believe there should be colocalization results on this page: Open Targets Genetics. I… --- ## ['Internal Server Error' on two pages for RSPO3](https://community.opentargets.org/t/internal-server-error-on-two-pages-for-rspo3/1440)
**Author:** [@mturchin20](https://community.opentargets.org/u/mturchin20)\ **Replies:** 2\ **Last updated:** [3 June 2024 16:26 UTC](https://community.opentargets.org/t/internal-server-error-on-two-pages-for-rspo3/1440 "2024-06-03T16:26:24Z")
Hi there, I’m getting an ‘Internal Server Error’ for two different CD pages off of RSPO3: a) Open Targets Genetics & b) Open Targets Genetics . Is there a recommended way for alternatively getting this data when this o… --- ## [GraphQL example: Cannot query field 'id' on type 'Tractability'. (line 16, column 7)](https://community.opentargets.org/t/graphql-example-cannot-query-field-id-on-type-tractability-line-16-column-7/1407)
**Author:** [@koryclick](https://community.opentargets.org/u/koryclick)\ **Replies:** 2\ **Last updated:** [23 April 2024 08:17 UTC](https://community.opentargets.org/t/graphql-example-cannot-query-field-id-on-type-tractability-line-16-column-7/1407 "2024-04-23T08:17:28Z")
Hello OT community team! I am using the Playground GraphQL and I noticed you have a no updated ‘link’ below the example code to run a GrapQL sample query. When I click on it, I redirects me to the Playground GraphQL … --- ## [GWAS Catalog results incorporation - backlog or other issue?](https://community.opentargets.org/t/gwas-catalog-results-incorporation-backlog-or-other-issue/1403)
**Author:** [@Joshua\_McElwee](https://community.opentargets.org/u/Joshua_McElwee)\ **Replies:** 2\ **Last updated:** [19 April 2024 14:42 UTC](https://community.opentargets.org/t/gwas-catalog-results-incorporation-backlog-or-other-issue/1403 "2024-04-19T14:42:20Z")
I was looking for GWAS results for a particular SNP for kidney-related phenotypes, and could not find the results in OT for the study (even though the study is in the GWAS catalog). This is a study from 2022 from the Su… --- ## [Bibliography not pulling out association between SOTORASIB and KRAS](https://community.opentargets.org/t/bibliography-not-pulling-out-association-between-sotorasib-and-kras/1394)
**Author:** [@Ellen\_McDonagh](https://community.opentargets.org/u/Ellen_McDonagh)\ **Replies:** 2\ **Last updated:** [10 April 2024 08:28 UTC](https://community.opentargets.org/t/bibliography-not-pulling-out-association-between-sotorasib-and-kras/1394 "2024-04-10T08:28:52Z")
Though SOTORASIB targets KRAS, it seems the bibliography pipeline is not extracting this relationship on either the drug page or gene page that I can see. There are not many publications yet (less than 30 from a quick pu… --- ## [API breaks for 'meddraSocCode' in drugWarnings](https://community.opentargets.org/t/api-breaks-for-meddrasoccode-in-drugwarnings/1380)
**Author:** [@janschultink](https://community.opentargets.org/u/janschultink)\ **Replies:** 1\ **Last updated:** [25 March 2024 09:52 UTC](https://community.opentargets.org/t/api-breaks-for-meddrasoccode-in-drugwarnings/1380 "2024-03-25T09:52:21Z")
This used to be a valid parameter in API calls for drug warnings, now it throws an error for an incorrect request. Easy to fix on the user end, but maybe prevent errors in existing code. Thank you for the great work. d… --- ## [Difference between parquet files and website/API](https://community.opentargets.org/t/difference-between-parquet-files-and-website-api/1349)
**Author:** [@fru](https://community.opentargets.org/u/fru)\ **Replies:** 3\ **Last updated:** [7 February 2024 13:12 UTC](https://community.opentargets.org/t/difference-between-parquet-files-and-website-api/1349 "2024-02-07T13:12:47Z")
Hi, I have downloaded the parquet files for “Associations - direct (by data type)” (Open Targets Platform). I have extracted information for a specific disease (MONDO\_0005277). When I compare the parquet files with the … --- ## [Differences between linkedDiseases and approvedIndications across versions](https://community.opentargets.org/t/differences-between-linkeddiseases-and-approvedindications-across-versions/1330)
**Author:** [@christosasi](https://community.opentargets.org/u/christosasi)\ **Replies:** 0\ **Last updated:** [18 January 2024 17:35 UTC](https://community.opentargets.org/t/differences-between-linkeddiseases-and-approvedindications-across-versions/1330 "2024-01-18T17:35:40Z")
Hi team, I have a query about differences in the ‘molecule’ and ‘indication’ datasets available on OpenTargets. My current understanding of these datasets is according to the schema of the OpenTargets datasets availabl… --- ## [Target Priorisation](https://community.opentargets.org/t/target-priorisation/1195)
**Author:** [@Sean\_Hackett](https://community.opentargets.org/u/Sean_Hackett)\ **Replies:** 5\ **Last updated:** [1 December 2023 10:38 UTC](https://community.opentargets.org/t/target-priorisation/1195 "2023-12-01T10:38:01Z")
Hi folks, I stumbled upon a new table “targetsPriorisation” which seems to have appeared in the 23.06 release (Index of /pub/databases/opentargets/platform/23.06/output/etl/json/targetsPriorisation). I didn’t see any me… --- ## [Difference between variant and gene pages](https://community.opentargets.org/t/difference-between-variant-and-gene-pages/1285)
**Author:** [@tzukuo](https://community.opentargets.org/u/tzukuo)\ **Replies:** 2\ **Last updated:** [23 November 2023 16:26 UTC](https://community.opentargets.org/t/difference-between-variant-and-gene-pages/1285 "2023-11-23T16:26:13Z")
Dear Open Target Community, My study is interested in the association between the variant 6\_41161514\_C\_T and TREM2. The variant’s page suggests a high V2G score, the influential effect, and a short distance between them… --- ## [Strange diseases in downloaded data](https://community.opentargets.org/t/strange-diseases-in-downloaded-data/1284)
**Author:** [@tzukuo](https://community.opentargets.org/u/tzukuo)\ **Replies:** 4\ **Last updated:** [21 November 2023 20:09 UTC](https://community.opentargets.org/t/strange-diseases-in-downloaded-data/1284 "2023-11-21T20:09:59Z")
Dear Open Targets Community, I downloaded OT Genetics data preprocessed by OT Platform to analyze them locally. However, the data include some strange disease descriptions (diseaseFrmSource): While the EFO code mean… [Previous page](https://community.opentargets.org/c/community-feedback/33.md) [Next page](https://community.opentargets.org/c/community-feedback/33.md?page=2)